Erk-1 Research advances

A previous study suggested that p38 can be a serine kinase for Stat-1 (23), and it’s widely recognized that phosphorylation on Ser727 is needed for its full transcriptional activity (5) without modifying its ability to bind to DNA (33). Our results imply that in macrophages, Ser727 phosphorylation occurs independently of activation of p38, in comparison

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