Hinokitiol reduces tumor metastasis by inhibiting heparanase via extracellular signal-regulated kinase and protein kinase B pathway.
Heparanase cleaves the extracellular matrix by degrading heparan sulfate that in the end results in cell invasion and metastasis; a situation that causes excessive mortality amongst most cancers sufferers. Many of the anticancer medicine obtainable right now are pure merchandise of plant origin, equivalent to hinokitiol. In the earlier report, it was revealed that hinokitiol
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