Day: June 27, 2021

    • Perfluorooctane sulfonate induces autophagy-associated apoptosis through oxidative stress and the activation of extracellular signal-regulated kinases in renal tubular cells

    Perfluorooctane sulfonate (PFOS) is amongst the most considerable natural pollution and is broadly distributed in the setting, wildlife, and people. Its poisonous results and organic hazards are related to its lengthy elimination half-life in people. However, the way it impacts renal tubular cells (RTCs) stays unclear. In this examine, PFOS was noticed to mediate the

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    • Extracellular signal-regulated kinase 1/2 is required for complement component C1q and fibronectin dependent enhancement of Fcγ- receptor mediated phagocytosis in mouse and human cells

    C1q is a soluble sample recognition protein that regulates a number of leukocyte capabilities, and deficiency in C1q outcomes in autoimmunity. C1q stimulates enhanced phagocytic perform by means of a number of mechanisms together with the speedy enhancement of Fcγ receptor (FcγR) -mediated phagocytosis. The molecular mechanism accountable for this speedy enhancement of phagocytic perform

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